Structure of PDB 5a2y Chain A

Receptor sequence
>5a2yA (length=468) Species: 9031 (Gallus gallus) [Search protein sequence]
KTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENR
GIHALIEFSEKSSVASLQAVTGIPKAAEHHVVPYKSRLFTFTLKNPGSQA
AEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLR
YLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHDKKGPF
EMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKF
SHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHG
LTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIG
GYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKE
VNKPESSPLYIWNPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKT
QQMINKEPWGLAAVLIPF
3D structure
PDB5a2y Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype.
ChainA
Resolution2.75 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) G283 G290 K298 I408 S465
Catalytic site (residue number reindexed from 1) G224 G231 K239 I349 S406
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UTP A S226 D239 N371 F372 S175 D188 N312 F313
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0002134 UTP binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016740 transferase activity
GO:0030145 manganese ion binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:1990817 poly(A) RNA polymerase activity
Biological Process
GO:0000965 mitochondrial RNA 3'-end processing
GO:0016070 RNA metabolic process
GO:0071044 histone mRNA catabolic process
Cellular Component
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0043231 intracellular membrane-bounded organelle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5a2y, PDBe:5a2y, PDBj:5a2y
PDBsum5a2y
PubMed26319014
UniProtF1NBW0

[Back to BioLiP]