Structure of PDB 5a0w Chain A

Receptor sequence

>5a0wA (length=182) [Search protein sequence]

ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAP
LMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMR
EQIAFIKGLYVAAGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLD
DHRHGVYVLNISLRDRIKFVHTILSSHLNPLP

3D structure

PDB

5a0w Structural and Dynamical Characterization of the I- Dmo Catalytic Activity

Chain

Resolution

2.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

3.1.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	D21 G22 Y25 Y29 K30 R33 R37 T41 K43 T76 R77 R124 T150 H152 D154 R157 S166 L167	D17 G18 Y21 Y25 K26 R29 R33 T37 K39 T72 R73 R120 T146 H148 D150 R153 S162 L163
BS02	dna	A	N32 R33 S34 E35 Y36 R37 S67 K68 Q70 R81 S83 S84 K85 A116 G118 D119 K120 R126 W128 K130 H158	N28 R29 S30 E31 Y32 R33 S63 K64 Q66 R77 S79 S80 K81 A112 G114 D115 K116 R122 W124 K126 H154
BS03	dna	A	K86 Y89 N93 R97	K82 Y85 N89 R93
BS04	MN	A	D21 A116	D17 A112

Gene Ontology

	Molecular Function
GO:0004519	endonuclease activity

	Biological Process
GO:0006314	intron homing
GO:0016539	intein-mediated protein splicing

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:5a0w, PDBe:5a0w, PDBj:5a0w
PDBsum	5a0w
PubMed
UniProt	P21505\|DMO1_DESMO Homing endonuclease I-DmoI

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