Structure of PDB 4zt1 Chain A

Receptor sequence
>4zt1A (length=209) Species: 9606 (Homo sapiens) [Search protein sequence]
PPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIE
RETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDN
KPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQD
PELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTT
ATAVITVTD
3D structure
PDB4zt1 Crystal Structure of Human E-Cadherin-EC1EC2 in Complex with a Peptidomimetic Competitive Inhibitor of Cadherin Homophilic Interaction.
ChainA
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A N102 N104 D134 D136 N143 D195 N98 N100 D130 D132 N139 D191
BS02 CA A E11 E69 D100 Q101 D103 D136 E7 E65 D96 Q97 D99 D132
BS03 CA A E11 D67 E69 D103 E7 D63 E65 D99
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4zt1, PDBe:4zt1, PDBj:4zt1
PDBsum4zt1
PubMed27120112
UniProtP12830|CADH1_HUMAN Cadherin-1 (Gene Name=CDH1)

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