Structure of PDB 4zrk Chain A

Receptor sequence
>4zrkA (length=292) Species: 10090 (Mus musculus) [Search protein sequence]
KTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIK
DTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFF
LQVKKQILDEKVYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELL
PKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGV
NYFTIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDK
EFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRR
3D structure
PDB4zrk Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
ChainA
Resolution2.316 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E136 L140 Y144 L176 Y177 Q178 M179 W191 E194 E117 L121 Y125 L157 Y158 Q159 M160 W172 E175
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0008092 cytoskeletal protein binding
Cellular Component
GO:0005856 cytoskeleton

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4zrk, PDBe:4zrk, PDBj:4zrk
PDBsum4zrk
PubMed26045165
UniProtP46662|MERL_MOUSE Merlin (Gene Name=Nf2)

[Back to BioLiP]