Structure of PDB 4zq0 Chain A

Receptor sequence
>4zq0A (length=234) Species: 658858 (Giardia lamblia P15) [Search protein sequence]
FTREDYVFMAQLNENAERYDEMVETMRKISGMEGELSDKERNLLSVAYKN
VIGPRRAAWRIVSSIEAKEKGRQKPNAKRIEQIRVYRQKIEKELSDICND
ILKLLQEQFVPRSTNADAKVFYYKMQGDYYRYLAEYSSGEDKEKIAGSAL
NAYNSAFEISQQLPPTHPIRLGLALNFSVFYYEILASPDRACELARKAFD
AAITDLDKLTEESYKDSTLIMQLLRDNLNLWVTD
3D structure
PDB4zq0 Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions.
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K53 R60 R135 Y136 L179 N180 N231 K49 R56 R131 Y132 L175 N176 N227
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005515 protein binding
GO:0019900 kinase binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0050815 phosphoserine residue binding
GO:0051219 phosphoprotein binding
Biological Process
GO:0000165 MAPK cascade
GO:0007165 signal transduction
GO:0008104 protein localization
GO:0030010 establishment of cell polarity
GO:0030036 actin cytoskeleton organization
GO:0051289 protein homotetramerization
GO:0051495 positive regulation of cytoskeleton organization
GO:0070207 protein homotrimerization
GO:0097298 regulation of nucleus size
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005819 spindle
GO:0005856 cytoskeleton
GO:0005930 axoneme
GO:0031514 motile cilium

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Cellular Component
External links
PDB RCSB:4zq0, PDBe:4zq0, PDBj:4zq0
PDBsum4zq0
PubMed26551337
UniProtE2RU97|1433_GIAIC 14-3-3 protein (Gene Name=GL50803_006430)

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