Structure of PDB 4zph Chain A

Receptor sequence
>4zphA (length=254) Species: 10090 (Mus musculus) [Search protein sequence]
ERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLTDQEL
KHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVH
PDDVDKLREQLSTSRRSFICRMRCPHFVVVHCTGYIKAFCLVAIGRLQVP
TEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRD
SFQQVVKLKGQVLSVMFRFRSKTREWLWMRTSSFTFQNPYSDEIEYIICT
NTNV
3D structure
PDB4zph Structural integration in hypoxia-inducible factors.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PRL A R266 V305 R121 V129 PDBbind-CN: -logKd/Ki=7.51,Kd=31nM
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4zph, PDBe:4zph, PDBj:4zph
PDBsum4zph
PubMed26245371
UniProtP53762|ARNT_MOUSE Aryl hydrocarbon receptor nuclear translocator (Gene Name=Arnt)

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