Structure of PDB 4znx Chain A

Receptor sequence
>4znxA (length=58) Species: 9606 (Homo sapiens) [Search protein sequence]
VTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYI
PSNYVAPV
3D structure
PDB4znx The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y91 Y93 D100 E116 G117 D118 W119 P134 N136 Y137 Y8 Y10 D17 E33 G34 D35 W36 P51 N53 Y54
BS02 peptide A S114 S115 W120 S135 S31 S32 W37 S52
External links
PDB RCSB:4znx, PDBe:4znx, PDBj:4znx
PDBsum4znx
PubMed27599862
UniProtP06241|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)

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