Structure of PDB 4znw Chain A

Receptor sequence
>4znwA (length=234) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHM
SNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLHA
3D structure
PDB4znw Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.31 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 V376 D538 L539 E542 I53 K57 V71 D221 L222 E225
BS02 OBM A L346 T347 E353 L387 M388 F404 V418 E419 G420 M421 I424 H524 L525 L41 T42 E48 L82 M83 F99 V113 E114 G115 M116 I119 H207 L208
External links
PDB RCSB:4znw, PDBe:4znw, PDBj:4znw
PDBsum4znw
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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