Structure of PDB 4znv Chain A

Receptor sequence
>4znvA (length=237) Species: 9606 (Homo sapiens) [Search protein sequence]
NSLALSLTADQMVSALLDAEPPILYSEYPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIR
HMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLHAP
3D structure
PDB4znv Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution1.771 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 V376 E380 D538 L539 E542 I54 K58 V72 E76 D223 L224 E227
BS02 4Q7 A M343 E353 L387 M388 L391 F404 G420 M421 I424 H524 L525 L540 M39 E49 L83 M84 L87 F100 G116 M117 I120 H209 L210 L225
External links
PDB RCSB:4znv, PDBe:4znv, PDBj:4znv
PDBsum4znv
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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