Structure of PDB 4znu Chain A

Receptor sequence
>4znuA (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLL
ILSHIRHMSNKGMEHLYSMVVPLSDLLLEMLDAHR
3D structure
PDB4znu Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 L372 V376 L379 D538 E542 M543 I53 K57 L67 V71 L74 D225 E229 M230
BS02 4Q9 A M343 T347 A350 E353 L387 L391 F404 V418 M421 I424 G521 H524 M38 T42 A45 E48 L82 L86 F99 V113 M116 I119 G212 H215
External links
PDB RCSB:4znu, PDBe:4znu, PDBj:4znu
PDBsum4znu
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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