Structure of PDB 4znt Chain A

Receptor sequence
>4zntA (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
YTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS
NKGMEHLYSMKCNVVPLSDLLLEMLDAHR
3D structure
PDB4znt Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution1.903 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 K362 L372 V376 E380 D538 L539 E542 I50 K54 L64 V68 E72 D219 L220 E223
BS02 OBB A M343 T347 E353 L387 M388 L391 F404 V418 E419 G420 M421 I424 G521 H524 L525 M528 M35 T39 E45 L79 M80 L83 F96 V110 E111 G112 M113 I116 G203 H206 L207 M210
External links
PDB RCSB:4znt, PDBe:4znt, PDBj:4znt
PDBsum4znt
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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