Structure of PDB 4zns Chain A

Receptor sequence
>4znsA (length=231) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TFLKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS
NKGMEHLYSMKNVVPLSDLLLEMLDAHRLHA
3D structure
PDB4zns Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution1.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 V376 D538 E542 I49 K53 V67 D218 E222
BS02 OFB A E353 M388 F404 V418 G420 M421 I424 H524 L525 M528 E44 M79 F95 V109 G111 M112 I115 H206 L207 M210
External links
PDB RCSB:4zns, PDBe:4zns, PDBj:4zns
PDBsum4zns
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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