Structure of PDB 4zn7 Chain A

Receptor sequence
>4zn7A (length=234) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB4zn7 Predictive features of ligand-specific signaling through the estrogen receptor.
ChainA
Resolution1.934 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 L372 V376 E380 D538 L539 E542 I54 K58 L68 V72 E76 D224 L225 E228
BS02 DES A M343 A350 E353 L387 F404 M421 H524 M39 A46 E49 L83 F100 M117 H210 BindingDB: Ki=0.128000nM,IC50=0.330000nM,EC50=0.110000nM
External links
PDB RCSB:4zn7, PDBe:4zn7, PDBj:4zn7
PDBsum4zn7
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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