Structure of PDB 4zir Chain A

Receptor sequence
>4zirA (length=263) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
GRIEVVNVSHIFHRGTPLEKKALENVSLVINEGECLLVAGNTGSGKSTLL
QIVAGLIEPTSGDVLYDGEKGYEIRRNIGIAFQYPEDQFFAERVFDEVAF
AVKNFYPDRDPVPLVKKAMEFVGLDFDSFKDRVPFFLSGGEKRRVAIASV
IVHEPDILILDEPLVGLDREGKTDLLRIVEKWKTLGKTVILISHDIETVI
NHVDRVVVLEKGKKVFDGTRMEFLEKYDPRFFTSKMLVMRRLVLKGEDPF
SMSDDELLERVCN
3D structure
PDB4zir ATP binding drives substrate capture in an ECF transporter by a release-and-catch mechanism.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A S47 Q85 D163 S47 Q83 D161
BS02 ANP A F12 T42 G45 K46 S47 T48 Q85 F12 T42 G45 K46 S47 T48 Q83
BS03 ANP A R134 F138 S140 G141 G142 E143 R132 F136 S138 G139 G140 E141
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0032217 riboflavin transmembrane transporter activity
GO:0042626 ATPase-coupled transmembrane transporter activity
Biological Process
GO:0032218 riboflavin transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0043190 ATP-binding cassette (ABC) transporter complex

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Cellular Component
External links
PDB RCSB:4zir, PDBe:4zir, PDBj:4zir
PDBsum4zir
PubMed26052893
UniProtQ9WY65|ECFA2_THEMA Energy-coupling factor transporter ATP-binding protein EcfA2 (Gene Name=ecfA2)

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