Structure of PDB 4zgn Chain A

Receptor sequence
>4zgnA (length=279) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
LVPRGSHMTLILTKNQVLHCQFSSWYSLFRKLTPKAKVIKPIPATVLKYL
HEDSIYVEQAYYPEREAIQLIEKAIKELGGAVVPKLNWSTPKDALWITTT
GSLKCTTAEEVLLLLKSSDFVAHDLNHAFDDCKDFDNADPKDFSFELVLK
EWFPMHASTEFRCFVKSKRLIAFCQRDDNYYEFLKENIDCYEKLISDLLK
KLDTFPDPDFVFDVYIHKDRAWLIDINPFYPRTDGLLFSWSELESMNSEN
MKPEIRLIPKASEGENLLEFAQKWQDLTN
3D structure
PDB4zgn Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP A K96 T101 K103 K164 W166 F167 M169 E174 R176 R190 I238 N241 K85 T90 K92 K150 W152 F153 M155 E160 R162 R176 I224 N227
BS02 MG A D239 N241 D225 N227
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0044183 protein folding chaperone
GO:0046872 metal ion binding
Biological Process
GO:0006457 protein folding
GO:1905143 eukaryotic translation initiation factor 2 complex assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4zgn, PDBe:4zgn, PDBj:4zgn
PDBsum4zgn
PubMed26211610
UniProtQ9P7N5|CD123_SCHPO Translation initiation factor eIF2 assembly protein (Gene Name=cdc123)

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