Structure of PDB 4zdb Chain A

Receptor sequence
>4zdbA (length=267) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
EIRQNEKISYRIEGPFFIIHLINPDNLNALEGEDYIYLGELLELADRNRD
VYFTIIQSSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVY
VTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSINDKVYLLYPFANL
GLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFNMPS
SNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVEVN
ESLKYWVDGEPLKRFRQ
3D structure
PDB4zdb Structures of yeast peroxisomal Delta (3), Delta (2)-enoyl-CoA isomerase complexed with acyl-CoA substrate analogues: the importance of hydrogen-bond networks for the reactivity of the catalytic base and the oxyanion hole.
ChainA
Resolution2.14 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A70 N101 L126 A129 F150 E158
Catalytic site (residue number reindexed from 1) A67 N98 L123 A126 F147 E155
Enzyme Commision number 5.3.3.8: Delta(3)-Delta(2)-enoyl-CoA isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CAA A D28 N29 L30 A32 F65 S68 D71 F72 K73 P149 N181 D25 N26 L27 A29 F62 S65 D68 F69 K70 P146 N178
Gene Ontology
Molecular Function
GO:0004165 delta(3)-delta(2)-enoyl-CoA isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0006631 fatty acid metabolic process
GO:0006635 fatty acid beta-oxidation
Cellular Component
GO:0005777 peroxisome
GO:0005782 peroxisomal matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4zdb, PDBe:4zdb, PDBj:4zdb
PDBsum4zdb
PubMed26527136
UniProtQ05871|ECI1_YEAST 3,2-trans-enoyl-CoA isomerase (Gene Name=ECI1)

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