Structure of PDB 4zbn Chain A

Receptor sequence
>4zbnA (length=97) Species: 9606 (Homo sapiens) [Search protein sequence]
EFSVCDSVSVWVGDKTTATDIKGKEVMVLGEVNISVFKQYFFETKCRDSG
CRGIDSKHWNSYCTTTHTFVKALTMDGKQAAWRFIRIDTACVCVLSR
3D structure
PDB4zbn Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor.
ChainA
Resolution2.447 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A E11 F12 V18 S19 V20 W21 Y52 F54 R59 R69 E1 F2 V8 S9 V10 W11 Y40 F42 R47 R52 PDBbind-CN: Kd=0.21nM
BS02 dna A I31 K32 F86 F101 I21 K22 F69 F84 PDBbind-CN: Kd=0.21nM
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding

View graph for
Molecular Function
External links
PDB RCSB:4zbn, PDBe:4zbn, PDBj:4zbn
PDBsum4zbn
PubMed26027732
UniProtP01138|NGF_HUMAN Beta-nerve growth factor (Gene Name=NGF)

[Back to BioLiP]