Structure of PDB 4z7w Chain A

Receptor sequence
>4z7wA (length=181) Species: 9606 (Homo sapiens) [Search protein sequence]
IVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLFR
RFRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVTL
GQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKIS
YLTFLPSADEIYDCKVEHWGLDEPLLKHWEP
3D structure
PDB4z7w Determinants of Gliadin-Specific T Cell Selection in Celiac Disease.
ChainA
Resolution2.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y9 Y22 R52 R53 F54 N62 V65 H68 N69 I72 V73 R76 Y9 Y23 R53 R54 F55 N63 V66 H69 N70 I73 V74 R77
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4z7w, PDBe:4z7w, PDBj:4z7w
PDBsum4z7w
PubMed25948817
UniProtQ30069

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