Structure of PDB 4z7v Chain A

Receptor sequence
>4z7vA (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
VADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLFRR
FRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVTLG
QPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISY
LTFLPSADEIYDCKVEHWGLDEPLLKHWEP
3D structure
PDB4z7v Determinants of Gliadin-Specific T Cell Selection in Celiac Disease.
ChainA
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y9 W43 R52 R53 F54 N62 V65 H68 N69 I72 R76 Y8 W43 R52 R53 F54 N62 V65 H68 N69 I72 R76
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4z7v, PDBe:4z7v, PDBj:4z7v
PDBsum4z7v
PubMed25948817
UniProtQ30069

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