Structure of PDB 4z6h Chain A

Receptor sequence
>4z6hA (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMK
DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM
SKERLLALKRSMS
3D structure
PDB4z6h LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4L2 A G43 F44 F45 F47 V49 I53 N100 Y106 G22 F23 F24 F26 V28 I32 N79 Y85 MOAD: Kd=612nM
PDBbind-CN: -logKd/Ki=6.21,Kd=612nM
External links
PDB RCSB:4z6h, PDBe:4z6h, PDBj:4z6h
PDBsum4z6h
PubMed25864491
UniProtQ9H8M2|BRD9_HUMAN Bromodomain-containing protein 9 (Gene Name=BRD9)

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