Structure of PDB 4z68 Chain A

Receptor sequence
>4z68A (length=155) Species: 9606 (Homo sapiens) [Search protein sequence]
SEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRV
SVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVAD
LWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDI
QDLLR
3D structure
PDB4z68 Hybrid Structural Analysis of the Arp2/3 Regulator Arpin Identifies Its Acidic Tail as a Primary Binding Epitope.
ChainA
Resolution1.859 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
2.4.2.30: NAD(+) ADP-ribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R525 S527 F532 G535 Y536 N537 L560 N565 Y569 H571 D589 W591 F593 E598 K602 R36 S38 F43 G46 Y47 N48 L71 N76 Y80 H82 D100 W102 F104 E109 K113
External links
PDB RCSB:4z68, PDBe:4z68, PDBj:4z68
PDBsum4z68
PubMed26774128
UniProtQ9H2K2|TNKS2_HUMAN Poly [ADP-ribose] polymerase tankyrase-2 (Gene Name=TNKS2)

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