Structure of PDB 4ytg Chain A

Receptor sequence
>4ytgA (length=417) Species: 242619 (Porphyromonas gingivalis W83) [Search protein sequence]
AFQETNPPAGPVRAIAEYERSAAVLVRYPFGIPMELIKELAKNDKVITIV
ASESQKNTVITQYTQSGVNLSNCDFIIAKTDSYWTRDYTGWFAMYDTNKV
GLVDFIYNRPRPNDDEFPKYEAQYLGIEMFGMKLKQTGGNYMTDGYGSAV
QSHIAYTENSSLSQAQVNQKMKDYLGITHHDVVQDPNGEYINHVDCWGKY
LAPNKILIRKVPDNHPQHQALEDMAAYFAAQTCAWGTKYEVYRALATNEQ
PYTNSLILNNRVFVPVNGPASVDNDALNVYKTAMPGYEIIGVKGASGTPW
LGTDALHARTHEVADKGYLYIKHYPILGEQDYKIEADVVSCANATISPVQ
CYYRINGSGSFKAADMTMESTGHYTYSFTGLNKNDKVEYYISAADNSGRK
ETYPFIGEPDPFKFTCM
3D structure
PDB4ytg Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase.
ChainA
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.5.3.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CYS A Y378 F424 T425 L427 C462 Y332 F378 T379 L381 C416
BS02 ARG A W127 D130 R152 R154 Y233 I234 H236 D238 T346 A351 W84 D87 R109 R111 Y190 I191 H193 D195 T303 A308
BS03 AZI A K248 E283 D456 K205 E240 D410
Gene Ontology
Molecular Function
GO:0004668 protein-arginine deiminase activity
Biological Process
GO:0009446 putrescine biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4ytg, PDBe:4ytg, PDBj:4ytg
PDBsum4ytg
PubMed26132828
UniProtQ9RQJ2|PAD_PORGI Peptidylarginine deiminase (Gene Name=PG_1424)

[Back to BioLiP]