Structure of PDB 4yrd Chain A

Receptor sequence
>4yrdA (length=341) Species: 158878 (Staphylococcus aureus subsp. aureus Mu50) [Search protein sequence]
MNIVITGAKGFVGKNLKADLTSTTDHHIFEVHRQTKEEELESALLKADFI
VHLAGVGSYLDHVLDILTRNTKKPAILLSSSIEQLLREYAEEYGNTVYIY
RWPNLFGKWCKPNYNSVIATFCYKIARNEEIQVNDRNVELTLNYVDDIVA
EIKRAIEGTPTIENGVPTVPNVFKVTLGEIVDLLYKFKQSRLDRTLPKLD
NLFEKDLYSTYLSYLPSTDFSYPLLMNVDDRGSFTEFIKTPDRGQVSVNI
SKPGITKGNHWHHTKNEKFLVVSGKGVIRFRHVNDDEIIEYYVSGDKLEV
VDIPVGYTHNIENLGDTDMVTIMWVNEMFDPNQPDTYFLEV
3D structure
PDB4yrd Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus.
ChainA
Resolution2.44 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H288 E295 H337 H260 E267 H309
BS02 3IT A F262 H288 F297 H337 M351 F234 H260 F269 H309 M323 MOAD: Kd=27uM
PDBbind-CN: -logKd/Ki=4.57,Kd=27uM
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4yrd, PDBe:4yrd, PDBj:4yrd
PDBsum4yrd
PubMed26471247
UniProtA0A0H3JP37

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