Structure of PDB 4yp1 Chain A

Receptor sequence
>4yp1A (length=178) Species: 10090 (Mus musculus) [Search protein sequence]
NVAHGLAWSYYIGYLRLILPGLQARIRMFNQLHNNMLSGAGSRRLYILFP
LDCGVPDNLSVVDPNIRFRDMLPQQNIDRAGIKNRVYSNSVYEILENGQP
AGVCILEYATPLQTLFAMSQDAKAGFSREDRLEQAKLFCRTLEEILEDVP
ESRNNCRLIVYQEPFSLSQEVLRHIRQE
3D structure
PDB4yp1 Structural Insights into the Distinct Binding Mode of Cyclic Di-AMP with SaCpaA_RCK.
ChainA
Resolution2.65 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2BA A G165 Y166 R237 Y239 P263 G13 Y14 R85 Y87 P111 PDBbind-CN: -logKd/Ki=5.04,Kd=9.1uM
Gene Ontology
Biological Process
GO:0002218 activation of innate immune response
GO:0032481 positive regulation of type I interferon production

View graph for
Biological Process
External links
PDB RCSB:4yp1, PDBe:4yp1, PDBj:4yp1
PDBsum4yp1
PubMed26171638
UniProtQ3TBT3|STING_MOUSE Stimulator of interferon genes protein (Gene Name=Sting1)

[Back to BioLiP]