Structure of PDB 4yos Chain A

Receptor sequence
>4yosA (length=340) Species: 9606,225400 [Search protein sequence]
EFTQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETF
CQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDM
SVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIE
VVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTC
EEVIFRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTL
VHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHV
YRSVLLKSEERGDLIKFYNTIYVGRVKSFALKYDPLSPFP
3D structure
PDB4yos Structural mechanisms of DREAM complex assembly and regulation.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y849 K853 F861 R869 S876 Y879 R880 N935 Y271 K275 F283 R291 S298 Y301 R302 N319
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:4yos, PDBe:4yos, PDBj:4yos
PDBsum4yos
PubMed25917549
UniProtL5LUA8;
P28749|RBL1_HUMAN Retinoblastoma-like protein 1 (Gene Name=RBL1)

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