Structure of PDB 4yoo Chain A

Receptor sequence
>4yooA (length=343) Species: 9606 (Homo sapiens) [Search protein sequence]
EFTQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETF
CQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDM
SVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIE
VVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTC
EEVIFRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTL
VHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHV
YRSVLLKEERGDLIKFYNTIYVGRVKSFALKYDLAPPLSPFPH
3D structure
PDB4yoo Structural mechanisms of DREAM complex assembly and regulation.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y849 K853 V854 F861 E863 R869 Y879 R880 I931 Y934 N935 Y271 K275 V276 F283 E285 R291 Y301 R302 I314 Y317 N318
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:4yoo, PDBe:4yoo, PDBj:4yoo
PDBsum4yoo
PubMed25917549
UniProtP28749|RBL1_HUMAN Retinoblastoma-like protein 1 (Gene Name=RBL1)

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