Structure of PDB 4yof Chain A

Receptor sequence
>4yofA (length=140) Species: 83331 (Mycobacterium tuberculosis CDC1551) [Search protein sequence]
DPDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRR
IGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPV
RSFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANAR
3D structure
PDB4yof Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A Y83 G84 F98 I103 V108 H113 P115 K116 G117 L118 G119 V120 S142 I143 F145 P146 H149 M152 Y171 Y23 G24 F38 I43 V48 H53 P55 K56 G57 L58 G59 V60 S82 I83 F85 P86 H89 M92 Y107
BS02 NO A F98 P115 Y171 F38 P55 Y107
External links
PDB RCSB:4yof, PDBe:4yof, PDBj:4yof
PDBsum4yof
PubMed25670859
UniProtP9WGK3|DEVS_MYCTU Oxygen sensor histidine kinase response regulator DevS/DosS (Gene Name=devS)

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