Structure of PDB 4ym2 Chain A

Receptor sequence
>4ym2A (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
PTFNPPVPYFGRLQGGLTARRTIIIKGYVPPTGKSFAINFKVGSSGDIAL
HINPRMGNGTVVRNSLLNGSWGSEEKKITHNPFGPGQFFDLSIRCGLDRF
KVYANGQHLFDFAHRLSAFQRVDTLEIQGDVTLSYVQI
3D structure
PDB4ym2 Structural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BGC A R240 E259 R55 E74 PDBbind-CN: -logKd/Ki=2.85,Kd=1400uM
BS02 SGA A H236 R240 N249 W256 E259 H51 R55 N64 W71 E74 PDBbind-CN: -logKd/Ki=2.85,Kd=1400uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:4ym2, PDBe:4ym2, PDBj:4ym2
PDBsum4ym2
PubMed26077389
UniProtP56470|LEG4_HUMAN Galectin-4 (Gene Name=LGALS4)

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