Structure of PDB 4yl6 Chain A

Receptor sequence
>4yl6A (length=88) Species: 9606 (Homo sapiens) [Search protein sequence]
LSASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQ
LYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDLE
3D structure
PDB4yl6 Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L299 M303 R307 S312 I315 Q316 F318 A319 L322 H323 Y325 R326 F356 L9 M13 R17 S22 I25 Q26 F28 A29 L32 H33 Y35 R36 F66
External links
PDB RCSB:4yl6, PDBe:4yl6, PDBj:4yl6
PDBsum4yl6
PubMed25982527
UniProtQ9BSQ5|CCM2_HUMAN Cerebral cavernous malformations 2 protein (Gene Name=CCM2)

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