Structure of PDB 4yjd Chain A

Receptor sequence
>4yjdA (length=342) Species: 9823 (Sus scrofa) [Search protein sequence]
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTPFTTTDVAAG
LWQPYTSEPSNPQEANWNQQTFNYLLSHIGSPNAANMGLTPVSGYNLFRE
AVPDPYWKDMVLGFRKLTPRELDMFPDYRYGWFNTSLILEGRKYLQWLTE
RLTERGVKFFLRKVESFEEVARGGADVIINCTGVWAGVLQPDPLLQPGRG
QIIKVDAPWLKNFIITHDLERGIYNSPLIIPGLQAVTLGGTFQVGNWNEI
NNIQDHNTIWEGCCRLEPTLKDAKIVGEYTGFGPVRPQVRLEREQLRFGS
SNTEVIHNYGHGGYGLTIHWGCALEVAKLFGKVLEERNLLAA
3D structure
PDB4yjd Crystal structure of DAAO variant
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) L51 G313 T317
Catalytic site (residue number reindexed from 1) L51 G313 T317
Enzyme Commision number 1.4.3.3: D-amino-acid oxidase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FAD A G7 A8 G9 V10 I11 A36 D37 R38 T44 T45 A48 A49 L51 K163 V164 T182 G281 G312 G313 Y314 G315 L316 T317 G7 A8 G9 V10 I11 A36 D37 R38 T44 T45 A48 A49 L51 K163 V164 T182 G281 G312 G313 Y314 G315 L316 T317
Gene Ontology
Molecular Function
GO:0003884 D-amino-acid oxidase activity
GO:0016491 oxidoreductase activity
GO:0071949 FAD binding
Biological Process
GO:0006562 proline catabolic process
GO:0007586 digestion
GO:0019478 D-amino acid catabolic process
GO:0036088 D-serine catabolic process
GO:0042416 dopamine biosynthetic process
GO:0046416 D-amino acid metabolic process
GO:0055130 D-alanine catabolic process
GO:0070945 neutrophil-mediated killing of gram-negative bacterium
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005777 peroxisome
GO:0005782 peroxisomal matrix
GO:0005829 cytosol
GO:0042995 cell projection
GO:0045202 synapse
GO:0048786 presynaptic active zone

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4yjd, PDBe:4yjd, PDBj:4yjd
PDBsum4yjd
PubMed
UniProtP00371|OXDA_PIG D-amino-acid oxidase (Gene Name=DAO)

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