Structure of PDB 4yiy Chain A

Receptor sequence
>4yiyA (length=577) Species: 185431 (Trypanosoma brucei brucei TREU927) [Search protein sequence]
SPLMDFFHSVEGRNYGELRSLTNETYQISENVRCTFLSIQSDPFAPGSQV
RLVCPCTFSLEKVLQTTDLAAANPCRRVAAEDFILRSFHAGYRNGIPRRT
SGAVQVLRPSQHVLERSTVGLVKEIEIFARVKLPGRRIDGHGAIDIFYNE
LVPLLEQCVVGLNEEDLHQHVICVHDQEELRSNLLGAGYVAFVANGAILP
RDAGNSDKPLRDNAVPFQSPKSLECSFTLPHSGKTITGMGLPPGLTLIAG
GGFHGKSTLLRALEVGIYNHVPDDGRTYVVVDPTAVKIRAEDRRSVHGVD
ISPFINNLPFGKTTNFFVTADASGSTSQAANIMEALELGSQLLLLDEDTC
ATNLMYRDALMQMLVPRAQEPITPFVERVADLSQNHGVSSIMVIGGSGQY
FPQARVVLVMNAYQISDCTKEAKEIASNSSSVFIPDVNRCFDPDGSFTTV
RTKVSGIGTESIRFSEETIDLSMVEQIVEEGQVNAIAQCLALLYDGERIV
PEMTTKGGALTQLPSPGGVCFNSNFSSMIAGCCSHQHDKRLELRTPSCYL
PRGFTSATRHIEIGAALNRLRTLRTVT
3D structure
PDB4yiy Structures of the T. brucei kRNA editing factor MRB1590 reveal unique RNA-binding pore motif contained within an ABC-ATPase fold.
ChainA
Resolution3.016 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A D384 S386 G387 S388 D321 S323 G324 S325
BS02 ANP A P263 V278 G315 F316 G318 K319 S320 T321 Y476 P200 V215 G252 F253 G255 K256 S257 T258 Y413
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000963 mitochondrial RNA processing
GO:0016554 cytidine to uridine editing
GO:0048255 mRNA stabilization
GO:0090615 mitochondrial mRNA processing
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0031019 mitochondrial mRNA editing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4yiy, PDBe:4yiy, PDBj:4yiy
PDBsum4yiy
PubMed26117548
UniProtQ57ZF2

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