Structure of PDB 4ygi Chain A

Receptor sequence
>4ygiA (length=150) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
QIIGTVPGVEVGDEFQYRMELNLLGIHRPSQSGIDYMKDDGGELVATSIV
SSGGYNDVLDNSDVLIYTGQGGNVGKKEPPKDQQLVTGNLALKNSINKKN
PVRVIRGIKKNYVYDGLYLVEEYWEETGSHGKLVFKFKLRRIPGQPELPW
3D structure
PDB4ygi Mechanistic insights into the recognition of 5-methylcytosine oxidation derivatives by the SUVH5 SRA domain
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
2.1.1.367: [histone H3]-lysine(9) N-methyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A Y378 R379 S391 Q392 G394 S413 G415 Y416 D418 Y428 T429 Q431 Y486 Y17 R18 S30 Q31 G33 S52 G54 Y55 D57 Y67 T68 Q70 Y112 PDBbind-CN: Kd=1.5uM
External links
PDB RCSB:4ygi, PDBe:4ygi, PDBj:4ygi
PDBsum4ygi
PubMed26841909
UniProtO82175|SUVH5_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5 (Gene Name=SUVH5)

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