Structure of PDB 4ydf Chain A

Receptor sequence
>4ydfA (length=116) Species: 11908 (Human T-cell leukemia virus type I) [Search protein sequence]
PVIPLDPARRPVIKAQVDTQTSHPKTIEALLDTGADMTVIPIALFSSNTP
LKNTSVLGAGGQTQDHFKLTSLPVLIRLPFRTTPIVLTSCLVDTKNNWAI
IGRDALQQCQGVLYLP
3D structure
PDB4ydf Privileged Structures Meet Human T-Cell Leukemia Virus-1 (HTLV-1): C2-Symmetric 3,4-Disubstituted Pyrrolidines as Nonpeptidic HTLV-1 Protease Inhibitors.
ChainA
Resolution2.804 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4B1 A D32 D36 M37 G58 A59 W98 D32 D36 M37 G58 A59 W98 PDBbind-CN: -logKd/Ki=5.10,Ki=7.9uM
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
GO:0008233 peptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4ydf, PDBe:4ydf, PDBj:4ydf
PDBsum4ydf
PubMed26000468
UniProtQ82134

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