Structure of PDB 4y7g Chain A

Receptor sequence
>4y7gA (length=277) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
LPLDTTWHRPGWTIGELEAAKAGRTISVVLPALNEEATIESVIDSISPLV
DGLVDELIVLDSGSTDDTEIRAIASGARVVSREQALPEVPVRPGKGEALW
RSLAATSGDIVVFIDSDLINPHPLFVPWLVGPLLTGEGIQLVKSFYRGRV
TELVARPLLAALRPELGCVLQPLSGEYAASRELLTSLPFAPGYGVEIGLL
IDTFDRLGLDAIAQVNLGVRAHRNRPLDELGAMSRQVIATLLSRCGIPDS
GVGLTQFLTRHTWPVSLVDRPPMKVMR
3D structure
PDB4y7g A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
ChainA
Resolution2.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.266: glucosyl-3-phosphoglycerate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D136 H258 D117 H222
BS02 G3P A G184 R185 H258 G148 R149 H222
BS03 UPG A P50 A51 L52 E54 S81 G113 K114 D134 S135 D136 L209 Y229 E232 H258 R259 R261 M269 P31 A32 L33 E35 S62 G94 K95 D115 S116 D117 L173 Y193 E196 H222 R223 R225 M233
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006011 UDP-glucose metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4y7g, PDBe:4y7g, PDBj:4y7g
PDBsum4y7g
PubMed26136334
UniProtP9WMW9|GPGS_MYCTU Glucosyl-3-phosphoglycerate synthase (Gene Name=gpgS)

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