Structure of PDB 4y7f Chain A

Receptor sequence
>4y7fA (length=279) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
PLDTTWHRPGWTIGELEAAKAGRTISVVLPALNEEATIESVIDSISPLVD
GLVDELIVLDSGSTDDTEIRAIASGARVVSREQALPEVPVRPGKGEALWR
SLAATSGDIVVFIDSDLINPHPLFVPWLVGPLLTGEGIQLVKSFYRGGRV
TELVARPLLAALRPELGCVLQPLSGEYAASRELLTSLPFAPGYGVEIGLL
IDTFDRLGLDAIAQVNLGVRAHRNRPLDELGAMSRQVIATLLSRCGIPDS
GVGLTQFLYTRHTWPVSLVDRPPMKVMRP
3D structure
PDB4y7f A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
ChainA
Resolution3.231 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.266: glucosyl-3-phosphoglycerate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D136 H258 D116 H222
BS02 48X A G184 R185 T187 H258 N260 G148 R149 T151 H222 N224
BS03 UPG A P50 A51 L52 E54 S81 G113 K114 D134 S135 D136 L209 Y229 E232 R256 H258 R259 R261 M269 P30 A31 L32 E34 S61 G93 K94 D114 S115 D116 L173 Y193 E196 R220 H222 R223 R225 M233
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006011 UDP-glucose metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4y7f, PDBe:4y7f, PDBj:4y7f
PDBsum4y7f
PubMed26136334
UniProtP9WMW9|GPGS_MYCTU Glucosyl-3-phosphoglycerate synthase (Gene Name=gpgS)

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