Structure of PDB 4xzj Chain A

Receptor sequence
>4xzjA (length=222) Species: 29497 (Vibrio splendidus) [Search protein sequence]
GPFDAIKQPNRSEEEVTQLAEDFKDWSKASNGWRYSFITANEKEAVEDFS
ISGYQTANDYLRATDTSTWGVAGADARQYIRTVKSALNKLPKYKGTAYRG
TWVKLSLLNKLEEGDVLVEPAFTSTSTLPEVAKRFSVVHPNSPQRLKRVL
FEVKINQGGHTIAGLSEYSKEAEVLFAPNAHFRITQIERTSNHTYIGVET
VKASAVKNTQKYNLYSGEEVEA
3D structure
PDB4xzj Characterization of Vis Toxin, a Novel ADP-Ribosyltransferase from Vibrio splendidus.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NAD A S68 Y72 N76 R80 R117 G118 T119 W120 S142 T143 A150 F153 L164 E189 E191 Y233 S50 Y54 N58 R62 R99 G100 T101 W102 S124 T125 A132 F135 L146 E171 E173 Y215 MOAD: Kd=95uM
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016757 glycosyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0090729 toxin activity
GO:0106274 NAD+-protein-arginine ADP-ribosyltransferase activity
Biological Process
GO:0035821 modulation of process of another organism
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4xzj, PDBe:4xzj, PDBj:4xzj
PDBsum4xzj
PubMed26352925
UniProtA3UNN4|VIS_VIBS1 Putative NAD(+)--arginine ADP-ribosyltransferase Vis (Gene Name=V12B01_18061)

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