Structure of PDB 4xz6 Chain A

Receptor sequence
>4xz6A (length=291) Species: 246200 (Ruegeria pomeroyi DSS-3) [Search protein sequence]
DSSDPIVIPIHNWSSQIVMSNVVGQIFEEMGVAVEFVTTDSQAVYESVRL
GDVTLELEVWEGAFGASFRAALEKGGIVDVGDHDAVTREDWWYPMWTKDA
CPGLPDWKALNDCAAVFATAETGDKGRYLDGPVDWLKHGKERVEALGMNF
EVINAGSAAALWAEIGAAEADKRPVVVFNWTPNFAEAVWPGEFVEFPEWV
DGCDKDPAVGPNPDALYDCGNPATGYLKKAAWEGMEAKWPDAYAVLTRIS
FTNPQIAEMAKLVDVDEMEPDEAAEAWLEANEDVWRPWLDG
3D structure
PDB4xz6 Mechanistic Insight into Trimethylamine N-Oxide Recognition by the Marine Bacterium Ruegeria pomeroyi DSS-3
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TMO A W55 W102 F106 E131 W177 F220 W222 W13 W60 F64 E89 W135 F178 W180 MOAD: Kd=1.6uM
BS02 CA A P249 V251 N254 A257 D260 P207 V209 N212 A215 D218
Gene Ontology
Molecular Function
GO:0022857 transmembrane transporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0043190 ATP-binding cassette (ABC) transporter complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xz6, PDBe:4xz6, PDBj:4xz6
PDBsum4xz6
PubMed26283766
UniProtQ5LT66|TMOX_RUEPO Trimethylamine N-oxide-binding protein (Gene Name=tmoX)

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