Structure of PDB 4xy9 Chain A

Receptor sequence
>4xy9A (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTEE
3D structure
PDB4xy9 9H-Purine Scaffold Reveals Induced-Fit Pocket Plasticity of the BRD9 Bromodomain.
ChainA
Resolution1.83 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 43U A W81 P82 F83 Q85 L92 N140 I146 W40 P41 F42 Q44 L51 N99 I105 MOAD: Kd=4651nM
PDBbind-CN: -logKd/Ki=5.33,Kd=4651nM
External links
PDB RCSB:4xy9, PDBe:4xy9, PDBj:4xy9
PDBsum4xy9
PubMed25703523
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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