Structure of PDB 4xy8 Chain A

Receptor sequence
>4xy8A (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMK
DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM
SKERLLALKRSMS
3D structure
PDB4xy8 9H-Purine Scaffold Reveals Induced-Fit Pocket Plasticity of the BRD9 Bromodomain.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 43U A F44 F47 V49 I53 N100 Y106 F23 F26 V28 I32 N79 Y85 MOAD: Kd=397nM
PDBbind-CN: -logKd/Ki=6.40,Kd=397nM
External links
PDB RCSB:4xy8, PDBe:4xy8, PDBj:4xy8
PDBsum4xy8
PubMed25703523
UniProtQ9H8M2|BRD9_HUMAN Bromodomain-containing protein 9 (Gene Name=BRD9)

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