Structure of PDB 4xxw Chain A

Receptor sequence
>4xxwA (length=229) Species: 10090 (Mus musculus) [Search protein sequence]
DDDCKLARGGPPATIVAIDEESRNGTILVDNMLIKGTAGGPDPTIELSLK
DNVDYWVLLDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCVNKKVGTV
IYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATD
IDDGPNGQIEYVIQYNPEDPTSNDTFEIPLMLTGNVVLRKRLNYEDKTRY
YVIIQANDRAQNLNERRTTTTTLTVDLEH
3D structure
PDB4xxw Tuning Inner-Ear Tip-Link Affinity Through Alternatively Spliced Variants of Protocadherin-15.
ChainA
Resolution2.261 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E27 E28 D83 D85 D121 E20 E21 D76 D78 D114
BS02 CA A E27 D85 D118 R119 D121 D159 E20 D78 D111 R112 D114 D152
BS03 CA A N120 N122 D157 D159 N163 D215 N113 N115 D150 D152 N156 D208
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007605 sensory perception of sound
GO:0048839 inner ear development
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0032420 stereocilium

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Cellular Component
External links
PDB RCSB:4xxw, PDBe:4xxw, PDBj:4xxw
PDBsum4xxw
PubMed29443515
UniProtQ99PJ1|PCD15_MOUSE Protocadherin-15 (Gene Name=Pcdh15)

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