Structure of PDB 4xx0 Chain A

Receptor sequence
>4xx0A (length=303) Species: 9823 (Sus scrofa) [Search protein sequence]
SYTASRKHLYVDKNTKVICQGFTGKQGTFHSQQALEYGTNLVGGTTPGKG
GKTHLGLPVFNTVKEAKEQTGATASVIYVPPPFAAAAINEAIDAEVPLVV
CITEGIPQQDMVRVKHRLLRQGKTRLIGPNCPGVINPGECKIGIMPGHIH
KKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDFTDCLE
IFLNDPATEGIILIGEIGGNAEENAAEFLKQHNSGPKSKPVVSFIAGLTA
PPGRRMGHAGAIIAGGKGGAKEKITALQSAGVVVSMSPAQLGTTIYKEFE
KRK
3D structure
PDB4xx0 Structure of GTP-specific succinyl-CoA synthetase in complex with CoA.
ChainA
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E217 H259
Catalytic site (residue number reindexed from 1) E216 H258
Enzyme Commision number 6.2.1.4: succinate--CoA ligase (GDP-forming).
6.2.1.5: succinate--CoA ligase (ADP-forming).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A G22 T24 G25 K26 Q27 P48 K50 Y79 V80 P81 T104 E105 C132 P133 G21 T23 G24 K25 Q26 P47 K49 Y78 V79 P80 T103 E104 C131 P132
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:4xx0, PDBe:4xx0, PDBj:4xx0
PDBsum4xx0
PubMed26249701
UniProtO19069|SUCA_PIG Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (Gene Name=SUCLG1)

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