Structure of PDB 4xre Chain A

Receptor sequence

>4xreA (length=108) Species: 3311 (Ginkgo biloba) [Search protein sequence]

ANTAFVSSACNTQKIPSGSPFNRNLRAMLADLRQNTAFSGYDYKTSRAGS
GGAPTAYGRATCKQSISQSDCTACLSNLVNRIFSICNNAIGARVQLVDCF
IQYEQRSF

3D structure

PDB

4xre A secreted protein with plant-specific cysteine-rich motif functions as a mannose-binding lectin that exhibits antifungal activity.

Chain

Resolution

2.597 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MAN	A	R93 E104	R93 E104

Gene Ontology

	Molecular Function
GO:0003779	actin binding
GO:0005537	D-mannose binding
GO:0019828	aspartic-type endopeptidase inhibitor activity

	Biological Process
GO:0006915	apoptotic process
GO:0012502	induction of programmed cell death
GO:0031640	killing of cells of another organism
GO:0042742	defense response to bacterium
GO:0050832	defense response to fungus

	Cellular Component
GO:0005576	extracellular region
GO:0005615	extracellular space

External links

PDB	RCSB:4xre, PDBe:4xre, PDBj:4xre
PDBsum	4xre
PubMed	25139159
UniProt	A4ZDL6\|GNK2_GINBI Antifungal protein ginkbilobin-2 (Gene Name=GNK2)