Structure of PDB 4xqu Chain A

Receptor sequence
>4xquA (length=318) Species: 1458555 (Influenza A virus (A/Jiangxi/IPB13/2013(H10N8))) [Search protein sequence]
DKICLGHHAVANGTIVKTLTNEQEEVTNATETVESTGINRLCMKGRKHKD
LGNCHPIGMLIGTPACDLHLTGMWDTLIERENAIAYCYPGATVNVEALRQ
KIMESGGINKISTGFTYGSSINSAGTTRACMRNGGNSFYAELKWLVSKSK
GQNFPQTTNTYRNTDTAEHLIMWGIHHPSSTQEKNDLYGTQSLSISVGSS
TYRNNFVPVVGARPQVNGQSGRIDFHWTLVQPGDNITFSHNGGLIAPSRV
SKLIGRGLGIQSDAPIDNNCESKCFWRGGSINTRLPFQNLSPRTVGQCPK
YVNRRSLMLATGMRNVPE
3D structure
PDB4xqu A Human-Infecting H10N8 Influenza Virus Retains a Strong Preference for Avian-type Receptors.
ChainA
Resolution3.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A R137 Q226 R128 Q219 PDBbind-CN: -logKd/Ki=6.07,Kd=0.86uM
BS02 SIA A Y98 T135 T136 R137 W153 H183 E190 Q226 Y88 T126 T127 R128 W144 H176 E183 Q219 PDBbind-CN: -logKd/Ki=6.07,Kd=0.86uM
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xqu, PDBe:4xqu, PDBj:4xqu
PDBsum4xqu
PubMed25766296
UniProtA0A059T4A1

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