Structure of PDB 4xqg Chain A

Receptor sequence

>4xqgA (length=474) Species: 1079 (Blastochloris viridis) [Search protein sequence]

DWPVYHRIDGPIVMIGFGSIGRGTLPLIERHFAFDRSKLVVIDPSDEARK
LAEARGVRFIQQAVTRDNYRELLVPLLTAGPGQGFCVNLSVDTSSLDIME
LARENGALYIDTVVEPWLGFYFDPDLKPEARSNYALRETVLAARRNKPGG
TTAVSCCGANPGMVSWFVKQALVNLAADLGVTGEEPTTREEWARLAMDLG
VKGIHIAERDTQRASFPKPFDVFVNTWSVEGFVSQGLQPAELGWGTFERW
MPDNARGHDSGCGAGIYLLQPGANTRVRSWTPTAMAQYGFLVTHNESISI
ADFLTVRDAAGQAVYRPTCHYAYHPCNDAVLSLHEMFGSGKRQSDWRILD
ETEIVDGIDELGVLLYGHGKNAYWYGSQLSIEETRRIAPDQNATGLQVSS
AVLAGMVWALENPNAGIVEADDLDFRRCLEVQTPYLGPVVGVYTDWTPLA
GRPGLFPEDIDTSDPWQFRNVLVR

3D structure

PDB

4xqg Comprehensive Structural Characterization of the Bacterial Homospermidine Synthase-an Essential Enzyme of the Polyamine Metabolism.

Chain

Resolution

1.417 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.5.1.44: homospermidine synthase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	NAD	A	G20 S21 I22 D45 P46 A65 V66 S92 V93 T95 T114 G160 A161 N162 P163 W229 S230 V400	G18 S19 I20 D43 P44 A63 V64 S90 V91 T93 T112 G158 A159 N160 P161 W227 S228 V398
BS02	1PS	A	S47 D48 E49 W348	S45 D46 E47 W346
BS03	1PS	A	M338 G342 K343 R344	M336 G340 K341 R342
BS04	AG2	A	R146 R191 D424	R144 R189 D422

Gene Ontology

	Molecular Function
GO:0016740	transferase activity
GO:0047296	homospermidine synthase activity
GO:0050514	homospermidine synthase (spermidine-specific) activity

View graph for
Molecular Function

External links

PDB	RCSB:4xqg, PDBe:4xqg, PDBj:4xqg
PDBsum	4xqg
PubMed	26776105
UniProt	O32323\|HSS_BLAVI Homospermidine synthase (Gene Name=hss)

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