Structure of PDB 4xq0 Chain A

Receptor sequence
>4xq0A (length=364) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
RLESENVKRLRQEKRLSLIVDLDQTIIHATVDPTVGEWMSDPGNVNYDVL
RDVRSFNLQEGPSGYTSCYYIKFRPGLAQFLQKISELYELHIYTMGTKAY
AKEVAKIIDPTGKLFQDRVLSADDSGSLAQKSLRRLFPCDTSMVVVIDDR
GDVWDWNPNLIKVVPYEFFVGIGDINSNFLGSNREALEEQNKERVTALEL
QKSERPLAKQQNALLEDPSHTLLHNRDHELERLEKVLKDIHAVYYEEEND
ISSRSGNHKHANVGLIIPKMKQKVLKGCRLLFSGVIPLGVDVLSSDIAKW
AMSFGAEVVLDFSVPPTHLIAAKIRTEKVKKAVSMGNIKVVKLNWLTESL
SQWKRLPESDYLLY
3D structure
PDB4xq0 Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A X170 D172 D298 X21 D23 D149
Gene Ontology
Molecular Function
GO:0004721 phosphoprotein phosphatase activity
GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Cellular Component
External links
PDB RCSB:4xq0, PDBe:4xq0, PDBj:4xq0
PDBsum4xq0
PubMed25883047
UniProtQ9P376|FCP1_SCHPO RNA polymerase II subunit A C-terminal domain phosphatase (Gene Name=fcp1)

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