Structure of PDB 4xpe Chain A

Receptor sequence
>4xpeA (length=246) Species: 928306 (Moloney murine leukemia virus isolate Shinnick) [Search protein sequence]
TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLG
IKPHIQRLLDQGILVPCQSPWNTPLLPVKDYRPVQDLREVNKRVEDIHPT
VPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPSGQ
LTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATS
ELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR
3D structure
PDB4xpe Structural basis for a six nucleotide genetic alphabet.
ChainA
Resolution1.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A Y64 P100 V101 R116 Y41 P77 V78 R88
BS02 dna A L99 D114 L115 R116 G191 L76 D86 L87 R88 G159
External links
PDB RCSB:4xpe, PDBe:4xpe, PDBj:4xpe
PDBsum4xpe
PubMed25961938
UniProtP03355|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

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