Structure of PDB 4xoa Chain A

Receptor sequence
>4xoaA (length=279) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPE
TITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTD
KPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYA
NNDVVVPTGGCDVSARDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYLSGT
TADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVSL
GLTANYARTGGQVTAGNVQSIIGVTFVYQ
3D structure
PDB4xoa Catch-bond mechanism of the bacterial adhesin FimH.
ChainA
Resolution2.541 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V163 A165 R166 D167 V168 V170 T171 L172 D174 Y175 Y256 A265 G266 N267 V268 Q269 S270 I271 I272 G273 V274 F276 V163 A165 R166 D167 V168 V170 T171 L172 D174 Y175 Y256 A265 G266 N267 V268 Q269 S270 I271 I272 G273 V274 F276
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005537 D-mannose binding
Biological Process
GO:0007155 cell adhesion
GO:0007638 mechanosensory behavior
GO:0031589 cell-substrate adhesion
GO:0043709 cell adhesion involved in single-species biofilm formation
Cellular Component
GO:0009289 pilus
GO:0009419 pilus tip
GO:0033644 host cell membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xoa, PDBe:4xoa, PDBj:4xoa
PDBsum4xoa
PubMed26948702
UniProtP08191|FIMH_ECOLI Type 1 fimbrin D-mannose specific adhesin (Gene Name=fimH)

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