Structure of PDB 4xo0 Chain A

Receptor sequence
>4xo0A (length=248) Species: 928306 (Moloney murine leukemia virus isolate Shinnick) [Search protein sequence]
TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLG
IKPHIQRLLDQGILVPCQSPWNTPLLPVYRPVQDLREVNKRVEDIHPTVP
NPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPEMGIS
GQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAA
TSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR
3D structure
PDB4xo0 Structural basis for a six nucleotide genetic alphabet.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y64 R116 Y41 R86
BS02 dna A L99 D114 L115 R116 G191 L76 D84 L85 R86 G161
External links
PDB RCSB:4xo0, PDBe:4xo0, PDBj:4xo0
PDBsum4xo0
PubMed25961938
UniProtP03355|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

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