Structure of PDB 4xmc Chain A

Receptor sequence
>4xmcA (length=184) Species: 13249 (Rhodnius prolixus) [Search protein sequence]
PGECSVNVIPKKNLDKAKFFSGTWYETHYLDMDPQATEKFCFSFAPRESG
GTVKEALYHFNVDSKVSFYNTGTGPLESNGAKYTAKFNTVDKKGKEIKPA
DEKYSYTVTVIEAAKQSALIHICLQEDGKDIGDLYSVLNRNKNALPNKKI
KKALNKVSLVLTKFVVTKDLDCKYDDKFLSSWQK
3D structure
PDB4xmc Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7.
ChainA
Resolution1.421 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.7.6.1: nitrite dismutase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM A E27 Y30 F41 F43 L58 H60 F69 N71 F88 Y107 I123 L135 S137 E26 Y29 F40 F42 L57 H59 F68 N70 F87 Y106 I122 L134 S136
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051381 histamine binding
GO:0070026 nitric oxide binding
Biological Process
GO:0033484 intracellular nitric oxide homeostasis
GO:0034776 response to histamine
GO:0042311 vasodilation
GO:0044552 vasodilation in another organism
GO:0050819 negative regulation of coagulation
GO:0070527 platelet aggregation
Cellular Component
GO:0005576 extracellular region

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Cellular Component
External links
PDB RCSB:4xmc, PDBe:4xmc, PDBj:4xmc
PDBsum4xmc
PubMed26167269
UniProtQ6PQK2|NP7_RHOPR Nitrophorin-7

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