Structure of PDB 4xm5 Chain A

Receptor sequence
>4xm5A (length=267) Species: 5478 (Nakaseomyces glabratus) [Search protein sequence]
EEFQQIPDFYGCYLLQSISKRQSFYIGSTPNPVRRLRQHNGSLSRRDGTR
PWEMVAIVYGFPSRIAALQFQHAWQHGYQTRYVKTRKGGRSIHHKLAMIT
SLLKNEYFRYMDLTLHFFNQKVEEIWKNDKFNVSQNNYTVSLSQDALTEI
NNDTIDDIMDVNEKNMELVQNLYSTTLAEKTKTLLLYKEKIDTGINTCQF
CNKIINLFAFCRDTSCTFVSHLACAYRYFMSNEDTIIPQSPKCPKCYTLL
KWCDVIYYSIKLNKDNT
3D structure
PDB4xm5 Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease.
ChainA
Resolution2.34 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C219 C222 H252 C255 C198 C201 H221 C224
BS02 ZN A C242 C247 C282 C211 C216 C246
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0008821 crossover junction DNA endonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
Cellular Component
GO:0005634 nucleus
GO:0033557 Slx1-Slx4 complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4xm5, PDBe:4xm5, PDBj:4xm5
PDBsum4xm5
PubMed25753413
UniProtQ6FML9|SLX1_CANGA Structure-specific endonuclease subunit SLX1 (Gene Name=SLX1)

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